Chromatin binding and N-terminal domains of DNMT3B1 confer specificity for developmentally regulated CpG island methylation
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CpG methylation in mammalian genomes is established by the closely related de novo DNA methyltransferases DNMT3A and DNMT3B. While both enzymes contribute to genome-wide CpG methylation, DNMT3B has a unique role in developmentally regulated CpG island (CGI) me... ...
