The Neuronal P2X7R Controversy: Revisiting Evidence, Methods, and Unresolved Questions
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The P2X7 receptor (P2X7R) is an ATP-gated ion channel belonging to the purinergic ligand-gated P2X receptor family. In the central nervous system (CNS), activation of this receptor has been proposed to play a key role in the pathogenesis of various neurodegene... ...