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TIR domain-containing proteins employ dual regulatory mechanisms to confer TaEDS1-dependent immunity in wheat

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The Toll/interleukin-1 receptor (TIR) domains are widely conserved across prokaryotes and eukaryotes. In plants, TIR nucleotide-binding leucine-rich repeat (TNL) proteins serve as the intracellular receptors that defend against pathogens. However, monocots lac... ...