Cytokine circuitry in pancreatic cancer: Targets for overcoming immune checkpoint inhibitor resistance in PDAC
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Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with a poor prognosis due to its complex and highly immunosuppressive tumor microenvironment (TME). The PDAC TME, characterized by dense desmoplasia and enhanced infiltration of immunosuppre... ...
