Control of Inositol 1,4,5-Trisphosphate Receptor Activity by Posttranslational Modifications
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Inositol 1,4,5-trisphosphate receptors (IP3Rs) are tetrameric calcium (Ca2+) release channels localized in the endoplasmic reticulum (ER), where they regulate cellular function by mediating local and global Ca2+ fluxes toward the cytosol, cell membrane, and or... ...