Therapeutic DNAzyme targeting conserved N gene sequences of pan-coronaviruses: Dual antiviral mechanisms of RNA cleavage and immune activation
{{output}}
Coronaviruses frequently mutate and cross species, rendering most strain-specific drugs and antibodies less effective and leaving familial-level threats unresolved. The nucleocapsid (N) protein, with highly conserved N- and C-terminal domains, plays a central ... ...
