Regio- and Stereoselective Synthesis of Polysubstituted γ-Lactams Enabled by Photocatalyzed Sequential Radical Aminoalkylation of MBH Acetates
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A visible-light photocatalytic method is reported for the regio- and stereoselective synthesis of polysubstituted γ-lactams from N-arylglycines and Morita-Baylis-Hillman (MBH) acetates. The reaction proceeds through sequential radical aminoalkylation of the d... ...
