4-Hydroxyderricin from Angelica keiskei promotes the stability of BRCA1 in triple-negative breast cancer cells through inhibition of cathepsin S
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Breast cancer susceptibility gene 1 (BRCA1), a tumor suppressor protein, is closely associated with ovarian and breast cancers. Previously, cathepsin S (CTSS) was reported to prevent BRCA1-mediated apoptosis, contributing to chemoresistance in TNBC. In this st... ...
