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Activation of a Locus Coeruleus to Ventral Tegmental Area Noradrenergic Pathway Blunts Binge-Like Ethanol Intake and Promotes Aversive Unconditioned Responses in TH-ires-Cre Mice

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Ethanol comprises innately aversive properties that may act as a deterrent to overconsumption. We have previously found that chemogenetic activation or inhibition of a noradrenergic locus coeruleus (LC) to rostromedial tegmental nucleus (RMTg) pathway bidirect... ...