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In Vivo Two-Photon Imaging Reveals Stochastic and Synchronized Extracellular Signal-Regulated Kinase Dynamics in Neurons of Awake Mice

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The neocortex is essential for higher-order brain functions such as cognition, perception, language, and motor control. Although extracellular signal-regulated kinase (ERK) activity in neurons has been well studied for its role in memory formation, its activit... ...