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Genome-wide CRISPR screening identifies Annexin A1 as a facilitator of porcine astrovirus entry

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Porcine astrovirus (PAstV) is an important and widespread pathogen in swine, linked to diarrheal outbreaks and extraintestinal disease. How PAstV enters host cells has remained unclear, and no cellular factor has been defined for PAstV entry. Here, a genome-wi... ...