Virus-based IFNγ gene delivery and photodynamic therapy cooperate to remodel the tumor microenvironment and suppress breast cancer
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This study demonstrates a potent synergistic anti-tumor effect of photodynamic therapy (PDT) based on chlorin e6 (Ce6) combined with Semliki Forest virus-mediated IFNγ (SFV/IFNγ) delivery in 4T1 mouse breast cancer model. We demonstrate that Ce6-PDT promotes... ...