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Evaluation of Classical and Modified Mixing Tests: Optimized Interpretation and a Structured Algorithm for Accurate Differentiation of the Causes of aPTT Prolongation

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Background: The activated partial thromboplastin time (aPTT) mixing test is widely used to investigate prolonged aPTT from factor deficiencies, inhibitors, or lupus anticoagulant (LA), but its interpretation remains challenging. ... ...