Strain-Release Asymmetric Multicomponent Reaction to Access Diverse N-α-Bisaryl-C3-quaternary Azetidines
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Azetidines are valuable motifs in drug discovery, yet access to densely substituted N-α-bisaryl-C3-quaternary azetidines remains limited. We report a strain-release multicomponent Petasis borono-Mannich reaction that enables the modular synthesis of N-α-bisa... ...
