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B cell-intrinsic IL-2 signaling regulates inflammation by promoting IL-10 expression in CD25+ age-associated B cells

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Interleukin (IL)-2 can impact both plasma cell (PC) differentiation and the generation of IL-10pos B cells. We generated mice bearing a B cell-specific deletion of Il2rb (Il2rbΔB) to define the B cell-intrinsic role of IL-2. Il2rbΔB mice displayed normal B c... ...