The MDM2-IL-33 Axis Promotes Gastric Tumorigenesis via K63 Ubiquitination-Dependent ERK/JNK Activation
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This study uncovers a novel post-translational regulatory mechanism through which MDM2 stabilizes IL-33 via K63-linked ubiquitination, thus facilitating the progression of gastric cancer. Using MKN45 and AGS gastric cancer cells, we conducted MDM2 knockdown fo... ...
