Synergistic Effects of Honokiol on Camptothecin-triggered Apoptosis of Drug-resistant Glioblastoma Cells via CDK1-mediated G2/M Arrest and Intrinsic ROS-Mitochondrion-dependent Pathway
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Background/aim: Temozolomide (TMZ) is the first-line drug for the treatment of glioblastoma multiforme (GBM). Unfortunately, most patients with GBM eventually develop drug resistance. Camptothecin (CPT) and honokiol (HNK) are bio... ...
