A Three-Layer Transformation Strategy toward Functionalized Fused Hydantoins and Diketopiperazines
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We present mAUCy (modified Asinger-Ugi cyclization), a scalable three-layer strategy enabling rapid synthesis of diverse thiazolo hydantoins and diketopiperazines. Beginning from 3-thiazolines via a modified Asinger reaction, followed by an Ugi-Joullié multic... ...
