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Gold-Catalyzed Carbonyl Release and its Adaptation for Prodrug Therapy Using Multivalent Lectin-Directed Artificial Metalloenzymes

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In the framework of developing artificial metalloenzyme (ArM) prodrug therapies, two main factors need to be considered; the cancer targeting capabilities of the ArM biocatalyst and the bioorthogonal prodrug activation mechanism. In this study, both these aspe... ...