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Influences of Ring Sizes and Chiral Substituents on Macrocyclic Chelators for Improving 68Ga Radiolabeling

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68Ga-labeled macrocyclic ligands have been extensively studied and used for positron emission tomography (PET) imaging. Compared with 12-membered DOTA derivatives, NOTA-based chelators with 9-membered macrocyclic rings exhibit more advantageous coordination st... ...