Prognostic and predictive impact of NOTCH1 mutations in patients with chronic lymphocytic leukemia: a tertiary single-center experience
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NOTCH1 mutations (NOTCH1m) occur in 6%-12% of newly diagnosed chronic lymphocytic leukemia (CLL) patients, increasing to 15%-20% in relapsed cases. Despite their clinical relevance, the independent prognostic impact of NOTCH1m remains controversial, particular... ...
