Singlet oxygen-precharged injectable hydrogel triggers ferroptosis and lactate metabolism reprogramming for enhanced colorectal cancer immunotherapy
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Photodynamic therapy (PDT) holds significant potential for tumor treatment, yet its immunotherapeutic efficacy is severely constrained by the immunosuppressive tumor microenvironment (TME) marked by lactate accumulation, hypoxia, and glutathione (GSH) overexpr... ...