Pathology associated with human CAR T cell administration in NOD.Cg- PrkdcscidIl2rgtm1Wjl/SzJ (NSG) mice: A retrospective analysis
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Chimeric antigen receptor (CAR) T-cell therapy is a promising treatment for neoplasia and autoimmune diseases. Immunocompromised mice are a common model to test the efficacy and safety of CAR T cells of human origin. Preclinical toxicity associated with human ... ...