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The Structural Analogy of MASP-2 with Thrombin and MASP-1 Reveals Strong Binding with PAR4

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Introduction: The historical discovery that thrombin activates Protease-Activated Receptor 4 (PAR4) has paved the way for several novel findings. Besides thrombin, the complement lectin pathway protease Mannose-Binding Lectin-Ass... ...