Nitrile-Imine Cross-Linking in Peptide Ions with Aromatic Amino Acid Residues: Are Ring-Stacking Interactions Important?
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Covalent conjugates of peptides containing aromatic amino acid residues Phe, Tyr, 3-nitro-Tyr, Trp, and 5-hydroxy-Trp with diaryltetrazole groups carrying 4-nitro and 4-methoxy substituents and linked to the peptide lysine were synthesized and used to study ph... ...