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Rosuvastatin Reduces Allostatic Overload due to Mechanical Strain: A New Finding on Vascular Remodeling Linked to Hypertension in Spontaneously Hypertensive Rats

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Introduction: Chronic hemodynamic overload due to hypertension produces cardiovas-cular remodeling, where mechanical stretch (MS) deformation, neurohumoral factors, and/or chronic interaction promote a harmful allostatic overload... ...