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Targeting the DDX3/PAF1 Axis Enhances Chemotherapy Efficacy in Pancreatic Ductal Adenocarcinoma

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Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy that has a poor survival rate of ∼13% with limited options for effective therapies. DDX3 is a member of the DEAD-box RNA helicase enzyme family. It acts as an adapter protein that interacts with s... ...