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Activated CD38+ mast cells promote gastric cancer progression by suppressing CD8+ T cell cytotoxic activity through adenosine metabolism

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Helicobacter pylori (H. pylori) infection is the primary driver in gastric cancer (GC) development, but the dynamic changes of the gastric mucosal microenvironment during H. pylori-associated GC progression remains elusive. Here, we perform single-cell RNA seq... ...