Automodification of N-terminal serine residues facilitates PARP2 release from DNA
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ADP-ribosyltransferases PARP1 and PARP2 are involved in DNA repair mechanisms and play a major role in detecting DNA damage. PARP1/2 enzymes transfer the ADP-ribosyl moiety from NAD+ to DNA damage response proteins, histones and to itself, activating the DNA r... ...
