Structural Basis for how Sialoglycan-binding Viridans Streptococci Accommodate Ligands that Exceed the Characterized Binding Site
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During endocardial infections, viridans group streptococci use proteins containing siglec-like binding regions to engage sialic acid-capped O- GalNAc glycans on platelet glycoprotein GPIbα. Much past work used isolated di-, tri-, or tetrasaccharide partial li... ...
