Deletion of Rspo1 or Rspo3 in the mesenchyme does not affect Wolffian duct maintenance or morphogenesis
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Secreted proteins, R-Spondin 1 (RSPO1) and R-Spondin 3 (RSPO3), potentiate WNT/β-catenin signaling that play critical roles in reproductive organ development. However, the functional significance of RSPO1 and RSPO3 in Wolffian duct development remains undefin... ...
