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Probing Macromolecular Interactions by Loss of Solvent Content in Protein Crystals: Application to the Amyloid‑β Peptide Binding to Transthyretin

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X-ray crystallography is commonly used to determine the structure of protein-protein complexes, revealing the atomic details of the interactions between macromolecules in the crystal. However, this technique has limited application in binary systems characteri... ...