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Exploring the Neurotherapeutic Potential of Bacillus-derived Macrolactins as NMDAR Antagonists for Alzheimer's disease: Network Pharmacology and Molecular Modeling Insights

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Background: The N-methyl-D-aspartate receptor (NMDAR) plays a critical role in regulating excitatory glutamatergic neurotransmission and synaptic plasticity. However, ex-cessive NMDAR activation can lead to increased calcium ion ... ...