Midkine (MDK) as a Central Regulator of the Tumor Microenvironment: From Developmental Cytokine to Therapeutic Target
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Midkine (MDK) is an oncofetal, heparin-binding cytokine that is re-expressed across diverse cancers and correlates with aggressive disease and treatment resistance. This review synthesizes current evidence on MDK as a coordinator of tumor-intrinsic signaling a... ...
