ALDH2 and NFκB Activation Restores VEGFR2 Expression and Angiogenesis Impaired by 4-HNE in Coronary Endothelial Cells
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4-hydroxy-2-nonenal (4HNE), a reactive aldehyde produced during lipid peroxidation, reduces angiogenesis in cultured mouse coronary endothelial cells (MCECs). In our previous studies, we found that 4HNE lowers both mRNA and protein levels of vascular endotheli... ...