Formulation and evaluation of a facile oral nanocarrier system Co-Encapsulating simvastatin and ezetimibe for enhanced Lipid-Lowering effect
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Simvastatin/Ezetimibe (SIM/EZE) is a widely prescribed hypolipidemic drug combination that provides substantial cardiovascular protection, particularly in high-risk patients. However, its poor dissolution and extensive first-pass metabolism limit gastrointesti... ...