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Friend or foe: New cytokine players in beta cell failure in type 1 diabetes mellitus

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Cytokines play a crucial role in autoimmune-mediated loss of pancreatic beta cells during type 1 diabetes (T1DM) development. The main diabetogenic cytokines IL-1β, TNFα and IFNγ, which were found to be profoundly upregulated in serum of T1DM-patients, are ... ...