The Dual Function Model Revisited by Thyroid Hormone Receptor Knockouts: Unliganded state controlling the initiation of adult organ development while liganded state ensuring larval tissue resorption during metamorphosis
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Thyroid hormone (T3) plays a critical role in vertebrate development, particularly in postembryonic organ remodeling and maturation. Plasma level of T3 peaks during postembryonic development, which corresponds to the neonatal period in mammals when most organs... ...
