Discovery of the thieno[2,3-b][1,4]thiazin-2(3H)-one STING inhibitors
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The adaptor molecule STING is embedded in the endoplasmic reticulum (ER) membrane. In innate immunity, STING is a critical cascade in regulating the cytoplasmic DNA-recognizing signaling. Aberrant STING signaling facilitates the host body to secrete an intoler... ...
