Spatiotemporal dynamic regulation of the CX3CL1-CX3CR1 axis: A double-edged sword in the tumor immune microenvironment and new strategies for precision therapy
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The CX3CL1-CX3CR1 signaling axis is a key yet functionally contradictory regulatory hub within the tumor immune microenvironment (TME), with its output shaped by spatiotemporal dynamics. This review seeks to address the core scientific question of how this axi... ...
