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Downregulation of OPCML is associated with activation of AKT signaling and aggressive phenotypes in glioblastoma cells

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Background: OPCML (opioid-binding protein/cell adhesion molecule-like), a glycosylphosphatidylinositol (GPI)-anchored IgLON adhesion molecule with brain-enriched expression, has tumor-suppressive roles in several epithelial cance... ...