Diastereoselective Synthesis of cis-α,α'-Disubstituted Cyclic Ethers via Borane-Catalyzed Reductive Cyclization of Diketones
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Cyclic ethers, particularly cis-α,α'-disubstituted tetrahydrofurans (THFs) and tetrahydropyrans (THPs), are prevalent motifs in bioactive compounds. However, efficient stereoselective methods for accessing such motifs remain limited. Herein, we report a dir... ...
