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Peptidoglycan architecture dictates protein interactions, tissue tropism, and arthritis in the Lyme disease spirochete Borrelia burgdorferi

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Lyme disease is a vector-borne illness transmitted by infected Ixodes spp. ticks. Dissemination of the Lyme spirochete-Borrelia burgdorferi-from the tick bite site results in a bi-phasic infection; the latter phase can cause severe musculoskeletal disease incl... ...