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Metabolic reprogramming during human neuron differentiation indicates glutaminase as a key determinant in Fragile X syndrome

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Metabolic homeostasis gone awry is a contributor to, if not an underlying cause of, several neurologic disorders. Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by a trinucleotide repeat expansion in FMR1 and consequent loss of the encoded pr... ...