Abnormal purinergic signaling contributes to development of renal cysts in autosomal dominant polycystic kidney disease
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Polycystic kidney diseases (PKD) are a group of inherited nephropathies marked by the formation of fluid-filled cysts along the nephron, which cause renal failure. Bulk RNA sequencing of microdissected renal cysts from Pkd1RC/RC mice identifies 4,970 different... ...