A size-exclusion chromatography fingerprinting workflow for the development of flow-through polishing operations for mAs continuous precipitation processes
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In this work we present a workflow for developing two-step, flow-through polishing processes for monoclonal antibodies (mAbs). The approach is demonstrated using redissolved precipitates from three CHO-derived mAbs generated by a continuous, PEG/ZnCl₂-mediate... ...