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Experimental evolution in the cystic fibrosis chemical environment reveals early TCA cycle flux as a central regulator of Mycobacterium abscessus biofilm formation

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Mycobacterium abscessus (MAB) is an emerging opportunistic pathogen that can cause severe, recalcitrant pulmonary infections in susceptible groups, including people with cystic fibrosis (CF). MAB forms biofilms during human infection and in environmental reser... ...