UBC9-mediated p53 SUMOylation drives tubular senescence and exacerbates acute kidney injury in mice
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The pathogenesis of acute kidney injury (AKI) is closely related to the senescence of renal tubular epithelial cells (RTECs). The role of small ubiquitin-like modification (SUMOylation) in cellular stress and senescence has been gradually elucidated. Recent ev... ...