PLN-L31A/I40A for the treatment of inherited heart disease caused by PLN-R14del mutations
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Phospholamban (PLN) is a regulatory protein of the SERCA2α calcium transporter, which plays an important role in maintaining calcium homeostasis in cardiomyocytes. Deletion of the 14th arginine of PLN (PLN-R14del) leads to dysregulation of SERCA2α and PLN ag... ...
