Shared HLA-E and Mamu-E Peptide Repertoires With Subtle Peptide Binding Differences Revealed by Combined nDSF- and Fluorescence Polarisation-Based Methods
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The primary function of MHC-E-human leukocyte antigen (HLA)-E in humans and Mamu-E in rhesus macaques-relates to immune surveillance via CD94/NKG2x receptors expressed on NK cells. However, a secondary role where MHC-E presents immunogenic peptides to CD8+ T c... ...